Neutrophils Functions in an Inflammatory Response of Periodontal Diseases

Background: Periodontal disease refers to any condition that affects the soft tissues, bones, cementum and ligaments that support teeth. Neutrophils in saliva are known to mediate tissue destruction in inflammatory diseases and kill pathogenic microbes through a cell death process known as NETosis. In the realm of periodontal research, the current standard for diagnosis involves the identification of reliable biomarkers for neutrophil mediators. These biomarkers can be utilized to diagnose periodontal disease effectively. The Aim: of this review is to outline the role of peptides neutrophils in periodontal disease. Methodology: in order to perform this study, relevant publications were searched for using keywords such as": periodontal disease, neutrophils, NETosis, inflammation, immune response." in the academic databases, Web of Science, PubMed, Scopus and Google Scholar. Conclusion: neutrophils play an important role in the response of inflammation in the periodontal disease.