Venom is present in most spiders in the world, only two groups of venomous spiders are known and their chemical composition varies greatly between species. The vast majority have venom that is not very toxic to the human body, as is the case with crabs. However, the venom of other spiders affects humans more seriously. This manuscript aims to verify the bionomics of spiders and their therapeutic potential (Arthropoda: Araneae). Regarding the type of research source, As for the type of research source, it was worked with scientific articles published in national and international magazines. This type of production is commonly the most valued in all bibliographic production and is the easiest to access. Access to articles was through virtual libraries such as SciELO, the University of São Paulo, Latin American Literature, and the University of Brasília. This library has a specific section for Hymenoptera, with journals and article texts available in full. Considering only this section constitutes a limitation of the study since articles belonging to journals that are part of other sections of the electronic library could also contribute to the discussion of the production of knowledge. However, in principle, within these articles, there could not necessarily be a discussion focused on biology, ecology, and taxonomy.