An inflammatory reaction is elicited by implants, which is critical for osseointegration. During the first phase of osseointegration, leukocyte-infiltrated blood coagulum fills the gaps surrounding implants. Reactive oxygen species are produced when polymorphonuclear neutrophils are quickly drawn to inflammatory areas and have been demonstrated to adhere to artificial implant surfaces in a matter of minutes. Neutrophils release their own DNA in response to infection and inflammation; this process is known as "neutrophil extracellular trap formation," or "NETosis." The function of neutrophil extracellular trap process in dental implants will be the main topic of this review.