Abstract: Block-chain is getting famous and one of the most widely recognized subjects can be thought of it has additionally changed the ways of life of many individuals in specific fields, in view of the effect on organizations and joins. Blockchain guarantees more dependable and fitting assets and it is exceptionally vital to remember that security and protection have a few deterrents as any innovation in this fields. The range of blockchain applications is extremely reached out into various regions in banking, wellbeing, car, the Internet of Things (IoT) and so forth. Numerous concentrates on focus on utilizing the block-chain information model in various executions. Motivated from these facts, in this paper, we present a systematic review of various blockchain- based solutions and their applicability in various Industry 4.0-based applications. In this paper, we attempt to portray block-chain innovation by talking about its model of information security and protection point of view with various agreement calculations, as well as issues and open doors in blockchains.