Review Article
Parasitic Diseases and the Role of Vector Insects
Majida Mohammad Abid Falhy, Ali Mousa Aakool, Yousif Karim Hussein, Zahraa Falah Azeez
Middle East Research Journal Microbiology and Biotechnology; 50-61.
https://doi.org/10.36348/merjmb.2025.v05i03.002
Vector-borne diseases are illnesses caused by pathogens transmitted to humans and animals through vectors such as parasites, viruses, and bacteria. More than 700,000 people die annually from diseases like malaria, dengue fever, schistosomiasis, African trypanosomiasis (sleeping sickness), leishmaniasis, Chagas disease, yellow fever, Japanese encephalitis, and onchocerciasis. These diseases predominantly affect populations in tropical and subtropical regions and disproportionately impact the poorest communities. Since 2014, major outbreaks of dengue fever, malaria, chikungunya, yellow fever and Zika virus have affected many populations, claimed lives and overwhelmed health systems in many countries. There are other diseases that cause chronic suffering, lifelong morbidity, disabilities and sometimes stigmatization, such as chikungunya, leishmaniasis and lymphatic filariasis. Medical Entomology is the scientific study of insects and arthropods that transmit diseases to humans and animals. It focuses on understanding the interactions between vectors (e.g., mosquitoes, flies, lice, fleas, ticks, and mites) and the pathogens they carry. For instance, mosquitoes transmit malaria parasites, while other arthropods like ticks can transmit pathogens causing diseases such as Lyme disease and babesiosis. Some arthropods also secrete toxins that can lead to neurological issues, allergies, infections, and eczema. The field of Medical Entomology was significantly advanced by the work of Sir Patrick Manson in the late 19th century. In 1878, Manson discovered that the filarial parasites responsible for lymphatic filariasis develop within mosquitoes before being transmitted to humans. This was one of the earliest demonstrations of a pathogen's development within an insect vector, marking a pivotal moment in the history of Medical Entomology.
Research Article
Serodiagnosis of Measles in Patients Attending a Tertiary Care Hospital in Visakhapatnam: A Retrospective Study
Dr Momidi Sai Jyothirmai
Middle East Research Journal Microbiology and Biotechnology; 62-68.
https://doi.org/10.36348/merjmb.2025.v05i03.003
Background: Measles remains a major public health concern in India, particularly among infants and young children, despite the existence of an established vaccination program. The disease continues to contribute significantly to morbidity and mortality, especially in resource-limited settings. Aim: This study aimed to assess the prevalence of measles-specific IgM antibodies in clinically suspected cases and to evaluate the demographic and clinical characteristics associated with seropositive results. Methods: A retrospective study was conducted over one year (January to December 2017) at King George Hospital, Visakhapatnam. Blood samples from 86 clinically suspected measles patients were tested for measles-specific IgM using an ELISA method. Patient data, including age, sex, vaccination status, and presenting symptoms, were recorded and analysed. Results: Out of 86 patients, 6 (6.9%) tested positive for measles-specific IgM antibodies. Among them, 4 were males and 2 were females, with a male-to-female ratio of 2:1. Two of the positive cases were infants aged below 6 months and were unvaccinated; the remaining four were adults aged 30-40 years with unknown immunization status. Fever was a universal symptom, and all positive cases belonged to low socioeconomic backgrounds. Conclusion: The findings indicate a significant burden of measles among infants too young to be vaccinated, highlighting the potential need for earlier immunization strategies. Strengthening routine immunization and targeted public health campaigns is essential to reduce measles incidence and associated complications.
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