Research Article
Assessment of the Characteristics of Hyperthermia in Human Health and Its Therapy
Marco Vinícios de Oliveira Santana, Carlos Henrique Marchiori, Klebert de Paula Malheiros, Érico Meirelles de Melo
Middle East Research Journal of Medical Sciences; 7-28.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.002
Hyperthermia is an increase in the body's core temperature caused by its inability to dissipate heat or reduce its production. The problem is serious and leads to the death of several people every year. One of its causes is exposure to excessive heat. On very hot days, for example, we must be careful to avoid the occurrence of the problem, drinking plenty of water and avoiding outdoor physical activities. This manuscript aims to evaluate the characteristics of hyperthermia in human health and its therapy. Data were collected using a quantitative and descriptive approach, through books and the following databases: SciVerse Scopus, Scientific Electronic Library Online (SciELO), and the Academic Search Tool (Scholar Google) Academia.edu., Researchgate, Library of Medicine and National Institute of Health – USA (PubMed) and Scientific, Latin American Literature in Health Sciences (LILACS). The search was developed using the subject descriptor, mosquito, diseases, filaria, hosts, transmission, diagnosis, and treatment referred to in journals, through a review of the literature on the subject. In the initial search, the titles and abstracts of the articles were considered for a broad selection of likely works of interest, with the abstracts being highlighted. The time frame was between 1999 and 2024, as we preferred to search for recent publications, and those that did not meet the established criteria were excluded. The search was conducted using the subject descriptors: “Cardiac system”, “Nervous system”, “Energy”, “Hydration, metabolism”, “Risk factors”, “Temperature,” “Thermoregulatory mechanism, “El Niño” and “Climate change”.
Research Article
Fatty Bacteria in the Intestine and Collagen Bacteria (Dominio: Bacteria Woese, Kandler & Wheelis 1990): Therapies and Biotechnology
Marco Vinícios de Oliveira Santana, Klebert de Paula Malheiros, Carlos Henrique Marchiori, Érico Meirelles de Melo
Middle East Research Journal of Medical Sciences; 29-48.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.003
Recent evidence has suggested that the intestinal microbiota is involved in energy regulation and the inflammatory process, an environmental factor related to the pathophysiology of obesity. The microbiota contains a variety of living microorganisms that colonize the intestine, and its development occurs throughout the life cycle from birth to adulthood. Collagen is one of these ingredients with functional characteristics. It is a protein of animal origin, whose function in the body is to contribute to the structural integrity of the tissues in which it is present. However, with the onset of adulthood, collagen deficiency begins to be noticed, as the body reduces its production, making its supplementation necessary. This review aims to study fatty bacteria in the intestine and collagen bacteria. Data were collected using a quantitative and descriptive approach, through books and the following databases: SciVerse Scopus, Scientific Electronic Library Online (SciELO), the Academic Search Tool (Scholar Google), Academia.edu., Researchgate, Library of Medicine and National Institute of Health (USA), (PubMed) and Scientific, Latin American Literature in Health Sciences (LILACS). The search was developed using the subject descriptor, mosquito, diseases, filaria, hosts, transmission, diagnosis, and treatment referred to in periodicals, through a literature review. In the initial search, the titles and abstracts of the articles were considered for the broad selection of likely works of interest, with the abstracts being highlighted.
Research Article
Investigation of Molecular Interaction in Binary Liquid Mixtures of some Cyclic Ether with N-Alkanols at 298.15K: By Ultrasonic Velocity Measurements
Dhirendra Kumar Sharma, Sandeep Sahu
Middle East Research Journal of Medical Sciences; 49-55.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.004
In the present study, we reported the densities and excess molar volumes and (V_m^E) excess acoustical impedance (ZE) for the pure organic solvent mixtures such as 1,3-Dioxolane + Pentanol, 1,3-Dioxolane + Hexanol, 1,3-Dioxolane + Heptanol, 1,3-Dioxolane + Octanol, 1,3-Dioxolane + Nonanol and 1,3-Dioxolane + Decanol at 298.15K. Excess molar volumes (V_m^E) excess acousticimpedance (ZE) for these binary mixtures were calculated from the experimental density and sound velocity data and fitted to the Redlich-Kister polynomial equation to check the accuracy of experimental data. In addition, the interactions between the unlike molecules in the mixtures were confirmed by using the experimental results. It has been observed that, weak dispersive type intermolecular interactions are confirmed in the systems investigated. Dipole inducement is found to be more predominant in the system. The results are interpreted in terms of molecular interaction between the components of the mixture.
Research Article
Relationship between Spirituality and Nutritional and Hormonal Processes
Marco Vinícios de Oliveira Santana, Carlos Henrique Marchiori, Klebert de Paula Malheiros, Érico Meirelles de Melo
Middle East Research Journal of Medical Sciences; 56-77.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.005
It is essential to many people's lives, providing meaning, connection, and balance. Likewise, nutrition plays a fundamental role in the health and well-being of the body. When these two aspects are combined consciously and intentionally, holistic wholeness and vitality can be achieved. Mindful eating involves choosing healthy foods, being present when eating, connecting with where your food comes from, and enjoying each meal. This simple act can become a spiritual practice, nourishing not only the body but also the soul. Some foods have traditionally been associated with spiritual and emotional benefits. For example, fresh, whole foods rich in nutrients can increase vitality and mental clarity, promoting elevated states of consciousness. The objective of this paper is to verify the relationship between spirituality and nutritional and hormonal processes. The methodology used an integrative literature review and a synthesis process to develop the study to expand the understanding of knowledge and achieve the expected results. Regarding the inclusion criteria, national and international articles were used in full, in Portuguese, English, and Spanish. The exclusion criteria were articles that were presented in duplicate and that did not meet the objectives of the investigation. In this way, the reviewer/researcher can prepare an integrative review with different purposes, which can be directed towards defining concepts, reviewing theories, or methodological analysis of included studies of a particular topic. In its construction process, it is necessary to go through six distinct stages, which are: identification of the theme and selection of the hypothesis or research question; establishment of criteria for inclusion and exclusion of studies/sampling or literature search; definition information to be extracted from selected studies/categorization of studies; evaluation of included studies; interpretation of results; and presentation of knowledge review/synthesis. To carry out the study, a search for scientific articles was carried out through Virtual Health Library, in SCIELO, LILACS, and Pubmed databases.
Research Article
Features and Presentations of Chronic Anal Fissure: A Study of 67 Cases
Dr. Mohammed Shamsur Rahman, Dr. Md. Rabeul Karim, Dr. Mohammad Khalilur Rahman, Dr. Kamrzzaman Al Mahmood, Dr. Marzia Akanda, Dr. Abu Bakar Md. Mostafa
Middle East Research Journal of Medical Sciences; 78-82.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.006
Background: Anal fissure, a longitudinal tear in the anoderm below the dentate line, is one of the most common benign anorectal conditions. The severe pain experienced during defecation, along with associated emotional stress, can significantly impact daily activities. As a result, it may considerably reduce an individual’s quality of life. Objective: To assess the features and presentations of chronic anal fissure. Methods: This was a prospective cross-sectional study conducted in the Department of Surgery, Jamalpur Medical College, Jamalpur, Bangladesh during the period from January 2023 to December 2023. A total of 67 patients with chronic anal fissures were enrolled purposively. Data were analyzed using MS Office tools. Results: The ages of the respondents ranged from 23 to 60 years, with a mean of 39.14 ± 8.77 years. Males comprised 52.0% and females 48.0%, with a male-to-female ratio of 1.08:1. Symptom duration varied from 1 to 13 years, averaging 5.92 ± 3.88 years. Anal pain was universal while bleeding, constipation, and skin tags occurred in 89.6%, 74.6%, and 64.2%, respectively. Posterior midline fissures were most common (64.2%). Conclusion: Chronic anal fissure predominantly affects middle-aged individuals, with a slight male predominance. Patients commonly experience prolonged symptoms, with anal pain as a universal complaint. Bleeding, constipation, and skin tags are frequent. The posterior midline is the most affected site, emphasizing the need for early diagnosis and appropriate management to prevent complications.
Research Article
Assessment of Radiation Protection Adherence and Support Services among Healthcare Professionals Working in Radiation Environment in Palestine
Walid Mahmoud Khalilia
Middle East Research Journal of Medical Sciences; 83-93.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.007
Radiation protection (RP) is crucial for safeguarding healthcare professionals in radiation circumstances. This survey aimed to evaluate RP adherence and the availability of support services among healthcare professionals working in Palestinian hospitals, distinguishing gaps and domains for improvement. A descriptive cross-sectional survey was conducted in six Palestinian hospitals, comprising (112) healthcare workers from diverse departments. A well-designed questionnaire assessed adherence to RP practices, availability of support services, and demographic characteristics. Data were analyzed using XLSTAT 2021, employing ANOVA and descriptive statistics. The results present that the response rate was (84.8%), overall adherence to RP guidelines was (75.6%), and with high level, usage of lead aprons (92%) and dosimeters (88.4%), but weak adherence to lead goggle usage (34.8%). However (95.5%) expressed willingness to attend radiation risk training, only (52.9%) reported enough RP support services, highlighting gaps in institutional resources and training. Occupation, gender, and department significantly affected levels of adherence, with males and radiologic technologists showing higher compliance (p< 0.05). Healthcare workers in Palestinian hospitals exhibit good adherence to RP guidelines, but significant gaps in training and support services persist. Addressing these shortages through boosting institutional support, implementing regular training programs. In addition to developing comprehensive RP policies and regulatory framework is critical to improving RP practices and ensure healthcare worker safety.
Research Article
Pre-operative Assessment of Difficult Laparoscopic Cholecystectomy by Clinico-Radiological Diagnosis
Dr. Md. Saiful Islam, Dr. Nelema Jahan, Dr. Mohammed Rafiqul Islam, Dr. S M Yunus Ali, Dr. Mohammad Salim, Dr. Iftakhar Al Mamun
Middle East Research Journal of Medical Sciences; 94-98.
DOI: https://doi.org/10.36348/merjms.2025.v05i01.008
Background: The gold standard in the treatment of symptomatic gallstones is laparoscopic cholecystectomy, which is one of the most regularly performed surgical operations globally. Ultrasonography is the most common noninvasive, safe, and highly accurate screening test for cholecystitis and cholelithiasis. It can also help surgeons to get an idea of potential difficulty to be faced during surgery in that particular patient. Objective: The objective of this study is to evaluate the role of USG of abdomen to detect the conditions of gall bladder in preoperative diagnosis and their per-operative comparison. Methods: A prospective cross-sectional study was conducted over a period of one and half year from January 2023 to June 2024. A total of 82 patients were included in this study. All Gall stones were diagnosed clinically and radiologically then compared with peroperative difficulties during laparoscopic cholecystectomy. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed by SPSS 29. Results: Most of the patients were female 54 (65.85%). Among them 35(42.68%) cases were present in 41-50 years of age group. Clinically >3 times attack were 58(70.73%). USG of whole abdomen revealed ≥4 mm wall thickness of gall bladder 39(47.56%), contracted gall bladder 41(50%), multiple stones were 61(74.39%) and impacted stones were 11(13.41%). In difficult gall bladder dissection time were > 1 hour 50(60.98%) and conversion to open needed 9(10.98%). Conclusion: The preoperative identification of cases of difficult laparoscopic cholecystectomy is an important advantage not only for the surgeon who has to perform the surgery, but also for the organization of the operating room and technical resources.
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