Research Article
Clinical Findings and Magnetic Resonance Imaging Findings in Lumbar Prolapsed Intervertebral Disc
A.K.M. Anowar Hossain, Md. Morshed Alam, Md. Nazrul Islam Mollah, Morshida Begum, A K Al Mira
Middle East Research Journal of Medical Sciences; 9-14.
DOI: 10.36348/merjms.2022.v02i01.002
Background: Low back pain (LBP) is a prevalent condition, with lumbar prolapsed intervertebral disc (PIVD) being a significant cause of radiculopathy and disability, especially in working-age individuals. PIVD results from disc degeneration or mechanical stress, often affecting the L4–L5 and L5–S1 levels. Clinical symptoms include radiating leg pain, sensory loss, and weakness. While neurological examination is essential, imaging, particularly Magnetic Resonance Imaging (MRI), is the gold standard for diagnosis. MRI must be interpreted alongside clinical findings, as disc abnormalities may appear in asymptomatic individuals. Correlating MRI features with clinical symptoms is crucial for accurate diagnosis and management. Aim of the study: The present study aims to evaluate and correlate the clinical and MRI findings among patients presenting with lumbar prolapsed intervertebral disc at a tertiary care hospital. Methodology: This hospital-based descriptive cross-sectional study was conducted over six months, from January to June 2022 in the Dept. of Radiology & Imaging, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. Fifty patients aged 18–70 years with low back pain, with or without radiculopathy, who underwent MRI, were enrolled using purposive sampling. Clinical evaluation included neurological examination, pain scoring (VAS), and straight leg raising (SLR) tests. MRI findings were analyzed for disc herniation level, type, and associated features. Data were collected using a structured sheet and analyzed using SPSS version 26.0. Descriptive statistics and chi-square tests were used to assess the correlation between clinical and MRI findings. Results: Among 50 patients, most were aged 31–50 years (68%) and male (64%), with 62% overweight/obese and 56% smokers. All presented with low back pain; 80% had radiculopathy, mainly right-sided (40%). Numbness and motor weakness were noted in 70% and 32%, respectively, with a mean VAS score of 6.9 ± 1.8. MRI revealed L4–L5 (48%) and L5–S1 (36%) as the most affected levels, with protrusions (42%) and paracentral herniations (56%) common. Nerve root compression was seen in 76%. Radiculopathy correlated with compression in 95%, and 85% of positive SLR cases matched MRI findings, confirming a strong clinical-radiological correlation. Conclusion: There was a significant correlation between clinical features and MRI findings of disc prolapse, consistent with findings from similar studies. However, not all imaging abnormalities corresponded to clinical symptoms, emphasizing the importance of correlating radiological findings with clinical evaluation for accurate diagnosis and management.
Research Article
Frequency of Diabetes Mellitus among Tuberculosis patients: An Observational study
Mohammad Syedul Islam, Fahmida Faizha Shama, Md. Ariful Islam, Ruhus Safa Noor
Middle East Research Journal of Medical Sciences; 15-19.
DOI: 10.36348/merjms.2022.v02i01.003
Introduction: Diabetes mellitus (DM) is a growing public health issue in tuberculosis (TB) endemic countries. The coexistence of TB and DM complicates management and worsens treatment outcomes. However, data from Bangladesh is limited. Objective: To investigate diabetes mellitus and its factors among TB patients receiving care in Dhaka City, Bangladesh. Materials and Methods: A cross-sectional study was conducted at various private hospital in Dhaka City, Bangladesh, from July to December 2020. A total of 35 adult tuberculosis (TB) patients were selected using a non-probability convenience sampling method. Data were collected through structured interviews and a review of medical records. Fasting blood glucose levels were measured to classify glycemic status according to the criteria set by the World Health Organization (WHO). Descriptive statistics were utilized to calculate the prevalence and examine associations across subgroups. Results: Among the 35 tuberculosis (TB) patients included in the study, 65.71% were male, and 34.29% were female. The majority of participants (82.86%) resided in urban areas, and 60% were from low socioeconomic backgrounds. A significant proportion of patients (45.71%) reported smoking, while 60% were physically inactive. Most patients were classified as normoglycemic (77.1%), with 14.3% prediabetic and 8.6% diabetic. These findings underscore the importance of glycemic screening in TB patients, as approximately 22.9% exhibit impaired glucose metabolism, which may require early intervention and management. Conclusion: Many TB patients in Dhaka have diabetes or prediabetes. Factors linked to glycemic issues include age, education, physical inactivity, and low BMI. These findings highlight the need for integrated DM screening and management in TB control programs.
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